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Auricular Acupressure as an Adjuvant Treatment for Wheezing in Stable Chronic Obstructive Pulmonary Disease
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Risk factors for recurrent wheezing following acute bronchiolitis: a 12-month follow-up

Lorena Cifuentes1, Solange Caussade, Claudia Villagrán

  • 1Ambulatory Service, Department of Pediatrics, School of Medicine, Catholic University of Chile, Lira 85, Santiago de Chile, 833-0074 Chile. lcifuen@med.puc.cl

Pediatric Pulmonology
|September 2, 2003
PubMed

Insights

Infants with respiratory syncytial virus (RSV) bronchiolitis, especially those hospitalized, experience more recurrent wheezing episodes. Risk factors for recurrent wheezing differ between RSV-positive and RSV-negative infants.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Respiratory Medicine

Background:

  • Bronchiolitis is a common respiratory infection in infants.
  • Recurrent wheezing after bronchiolitis is a significant concern.
  • Respiratory syncytial virus (RSV) is a primary cause of bronchiolitis.

Purpose of the Study:

  • To identify wheezing recurrences in infants with RSV-positive and RSV-negative bronchiolitis.
  • To determine risk factors associated with recurrent wheezing in these infant groups.
  • To compare the incidence and predictors of wheezing episodes post-bronchiolitis.

Main Methods:

  • A 1-year prospective cohort study involving infants under 2 years old.
  • Monthly follow-up (clinical visits/telephone) to record wheezing episodes and risk factors.
  • RSV enzyme immunoassay to categorize infants into RSV+ and RSV- groups.

Main Results:

  • RSV+ infants had a higher mean number of wheezing recurrences (3.36/year) compared to RSV- infants (2.34/year).
  • Hospitalization during acute RSV bronchiolitis was a significant risk factor for recurrent wheezing in RSV+ infants.
  • In RSV- infants, male gender, number of siblings, and daycare attendance were associated with recurrent wheezing.

Conclusions:

  • RSV-proven bronchiolitis, particularly when requiring hospitalization, is linked to increased recurrent wheezing in the following 12 months.
  • Distinct risk factors contribute to recurrent wheezing in RSV+ and RSV- infant populations.
  • Further research may explore underlying mechanisms like airway hyperreactivity in RSV+ infants.

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