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Regression of cutaneous intravascular lymphoma with rituximab
Karen Han1, Jennifer C Haley, Keith Carlson
1Division of Dermatology, University of California at Los Angeles, USA.
Cutis
|September 5, 2003
Abstract:
Intravascular lymphoma, also known as malignant angioendotheliomatosis or angiotropic lymphoma, is a rare non-Hodgkin lymphoma that is usually fatal. It often presents with cutaneous and/or nervous system involvement, but the disease can involve any organ system. Clinical symptoms result from the occlusion of small vessels by tumor cells and fibrin. We present a case of cutaneous intravascular lymphoma successfully treated with rituximab, a recombinant antibody to CD20 antigen found on B lymphocytes.