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The antimicrobial activity of non-antibiotics: interactions with antibiotics
1Hôpital Cochin, Hepato-gastro-enterology Dpt., Paris, France.
APMIS. Supplementum
|January 1, 1992
Abstract:
The following are considered: the direct antibacterial activity of non-antibiotics: resistance-reversing agents and resistance-inducing agents; the antibacterial and antiparasitic activity of non-antibiotics: psychotropics, antihistaminics, antineoplastics, allopurinol, hyperbaric oxygen, etc.; as well as the antibacterial activity of agents modifying the urinary pH; the influence of non-antibiotic drugs on the pharmacokinetic parameters of antibiotics; the anti infectious activity of non-antibiotics through their effects on host defences, immunity and inflammation, and finally the use of non-antibiotics to decrease the toxicity of anti-infectious agents.