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Myocardial bridging in adult patients with hypertrophic cardiomyopathy

Paul Sorajja1, Steve R Ommen, Rick A Nishimura

  • 1Division of Cardiovascular Disease and Internal Medicine, Mayo Clinic and Foundation, 200 SW First Street, Rochester, MN 55905, USA.

Journal of the American College of Cardiology
|September 6, 2003
PubMed

Insights

Myocardial bridging in adult hypertrophic cardiomyopathy (HCM) patients does not increase the risk of sudden cardiac death or other mortality. This finding suggests bridging is not a significant prognostic factor in this population.

Area of Science:

  • Cardiology
  • Cardiovascular Research
  • Clinical Investigation

Background:

  • Myocardial bridging is linked to adverse outcomes in pediatric hypertrophic cardiomyopathy (HCM).
  • The prognostic significance of myocardial bridging in adult HCM patients remains unclear.

Purpose of the Study:

  • To investigate the association between myocardial bridging and mortality risk in adult patients diagnosed with HCM.
  • To determine if myocardial bridging impacts sudden cardiac death and overall mortality in this patient group.

Main Methods:

  • Retrospective analysis of coronary angiograms from 425 adult HCM patients.
  • Assessment for myocardial bridging and comparison of survival rates between patients with and without bridging.
  • Clinical follow-up to evaluate all-cause mortality, cardiac death, and sudden cardiac death.

Main Results:

  • Myocardial bridging was identified in 15% (64 patients) of the study cohort.
  • No significant difference in survival free of all-cause mortality, cardiac death, or sudden cardiac death was observed between groups.
  • Neither the presence nor characteristics of myocardial bridging predicted a poorer outcome in univariate or multivariate analyses.

Conclusions:

  • Adult patients with HCM and diagnosed myocardial bridging do not face an elevated risk of death, including sudden cardiac death.
  • Myocardial bridging appears to be a benign finding in adult HCM patients regarding mortality risk.
Abstract

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