Related Experiment Videos
Non-A, non-B viral hepatitis in Egypt.
M A Darwish1, M Shaker, A M al-Kady
1Ain Shams University, Faculty of Medicine, Cairo, Egypt.
The Journal of the Egyptian Public Health Association
|January 1, 1992
Summary
Hepatitis B virus (HBV) caused most acute viral hepatitis cases in young adults. Other causes included Hepatitis A virus (HAV), Epstein-Barr virus (EBV), Cytomegalovirus (CMV), and undiagnosed Non-A, non-B hepatitis.
Area of Science:
- Hepatology
- Virology
- Infectious Diseases
Background:
- Acute viral hepatitis is a significant global health concern.
- Etiology of acute viral hepatitis can be diverse, including Hepatitis A, B, Epstein-Barr, and Cytomegalovirus infections.
- Non-A, non-B hepatitis remains a diagnostic challenge.
Purpose of the Study:
- To investigate the etiological agents of acute viral hepatitis in young adults.
- To determine the prevalence of Hepatitis A virus (HAV), Hepatitis B virus (HBV), Epstein-Barr virus (EBV), and Cytomegalovirus (CMV) infections.
- To identify cases of Non-A, non-B hepatitis by exclusion.
Main Methods:
- ELISA technique was used to detect HBsAg, IgM anti-HBc, IgM anti-HAV, and IgM anti-CMV.
- Monospot slide test was employed to diagnose infectious mononucleosis caused by EBV.
- Non-A, non-B hepatitis was diagnosed by excluding other identified viral causes.
Main Results:
- Hepatitis B virus (HBV) was the most common cause, identified in 66.5% of patients.
- Hepatitis A virus (HAV) accounted for 4.5% of cases.
- Epstein-Barr virus (EBV) and Cytomegalovirus (CMV) were identified in 3.5% and 1% of cases, respectively.
- Non-A, non-B hepatitis constituted 24.5% of the acute viral hepatitis cases.
Conclusions:
- Hepatitis B virus is the predominant cause of acute viral hepatitis in this young adult population.
- A significant proportion of acute viral hepatitis cases remain undiagnosed or attributed to Non-A, non-B hepatitis.
- Comprehensive etiological investigation is crucial for managing acute viral hepatitis.