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Clinical evaluation of a novel liquid tooth whitening gel
Gianluca Gambarini1, Luca Testarelli, Giovanni Dolci
1Dental School, University of Rome, La Sapienza, Italy. ggambarini@tin.it
Purpose:
To clinically evaluate a new system for at-home tooth whitening (Colgate Simply-White Whitening Gel), by comparing tooth color improvement and adverse event incidence after 14-days treatment.
Materials And Methods:
22 subjects (aged 21-46 years) were enrolled into the study. Tooth color and safety assessments were conducted at baseline and following a 2-week at-home treatment. Efficacy was assessed using VITA shade scores. Safety evaluations were performed including the examination of plaque index (PI), bleeding index (BOP), gingival recession and dentin hypersensitivity. Statistical analysis was performed to determine the mean change from baseline.
Results:
The new whitening gel releasing 5.9% hydrogen peroxide was significantly effective in lightening tooth shade. After only 2 weeks, patients enrolled in the study exhibited an overall mean 3.56-shade improvement from baseline, far superior than minimum values established in ADA Guidelines for the acceptance of peroxide-containing oral hygiene products. Periodontal health (PI and BOP) improved with time overall. Dentin hypersensitivity slightly increased, but it was very well tolerated. No patient discontinued study participation due to such an adverse event. Therefore, it was concluded that the new Colgate Simply White Clear Whitening Gel provided clinically proven, safe and effective at-home tooth whitening.