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Secondary structure analysis identifies a putative mouse protein demonstrating similarity to the repeat units found
K Duff1, J Parsons, T C Hodgman
1Department of Medicine, University of Cambridge, UK.
DNA Sequence : the Journal of DNA Sequencing and Mapping
|January 1, 1992
Abstract:
The predicted protein product of an anonymous clone isolated from a cDNA library prepared from 12 day post coitum (p.c) embryonic mouse heart tissue demonstrated the same segmental repeats previously identified in the cell division control protein, CDC4 and the G protein beta 1 subunit. A search of the protein database subsequently identified three other classes of protein containing the repeat. Secondary structure analyses performed on the repeat sequences revealed a high degree of conservation suggesting that the repeat motif performs a specific function in a diverse range of proteins.