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Related Experiment Videos

Diffusion-weighted MR imaging in intracranial infections.

C C Lim1, W Lee, S M Chng

  • 1Department of Neuroradiology, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433. tchoyoson_lim@notes.ttsh.gov.sg

Annals of the Academy of Medicine, Singapore
|September 13, 2003
PubMed
Summary

Diffusion-weighted MRI (DWMRI) aids in diagnosing intracranial infections by showing distinct lesion appearances. This technique enhances lesion visibility, proving valuable for assessing central nervous system infections.

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Area of Science:

  • Neurology
  • Radiology
  • Infectious Diseases

Background:

  • Diffusion-weighted magnetic resonance (MR) imaging (DWMRI) is a valuable tool for assessing acute cerebral infarction.
  • Its utility extends to other central nervous system (CNS) diseases, including intracranial infections.

Purpose of the Study:

  • To present the DWMRI appearance of various intracranial infections.
  • To evaluate DWMRI's effectiveness in lesion conspicuity and assessment of CNS infections.

Main Methods:

  • Reviewed 30 patients with clinically diagnosed CNS infections.
  • All patients underwent conventional contrast-enhanced MR and DWMRI (b = 1000 s/mm2) using single-shot echo-planar imaging.

Main Results:

  • Intracranial infections like abscesses and tuberculomas appeared hyperintense on DWMRI.

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  • Neurocysticercosis lesions were hypointense, while encephalitis and toxoplasmosis showed variable DWMRI signal intensities.
  • Meningitis without parenchymal involvement was not detected by DWMRI, though one case of tuberculous meningitis showed infarction.

    • Conclusions:

    • DWMRI enhances lesion conspicuity in cerebral infections.
    • Distinct DWMRI appearances were observed for different infectious organisms and diseases, aiding in diagnosis.