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Updated: Aug 18, 2026

Rodent Model of Intestinal Ischemia-Reperfusion Injury via Occlusion of the Superior Mesenteric Artery
Published on: October 20, 2023
Mesenteric ischemia
1Section of Digital Imaging, Department of Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.
Abstract:
Mesenteric ischemia is an important clinical condition becoming more prevalent with aging of the population. Mesenteric ischemia may be manifest in an acute presentation, usually secondary to thromboembolism or cardiac insufficiency. Patients have abdominal pain, lactic acidosis, benign abdominal examination, and, often, coexistent multisystem organ dysfunction. Chronic mesenteric ischemia is secondary to proximal arterial stenosis or occlusions inadequately compensated by collateral flow. Clinical presentation may simulate occult malignancy. In this review article, the role of Doppler sonography and other diagnostic imaging tests in suspected acute mesenteric ischemia and mesenteric arterial insufficiency are evaluated with emphasis on diagnostic criteria and appropriate use in each clinical context.
Insights
Mesenteric ischemia, a growing concern in aging populations, presents acutely with pain and lactic acidosis or chronically mimicking malignancy. This review evaluates diagnostic imaging, including Doppler sonography, for mesenteric arterial insufficiency.
Area of Science:
- Vascular Surgery
- Diagnostic Imaging
- Gastroenterology
Background:
- Mesenteric ischemia is increasingly prevalent due to population aging.
- Acute mesenteric ischemia often presents with abdominal pain, lactic acidosis, and organ dysfunction.
- Chronic mesenteric ischemia can mimic malignancy due to arterial stenosis.
Purpose of the Study:
- To review the role of diagnostic imaging in suspected acute mesenteric ischemia.
- To evaluate imaging modalities for mesenteric arterial insufficiency.
- To emphasize diagnostic criteria and clinical application.
Main Methods:
- Review of current literature on diagnostic imaging for mesenteric ischemia.
- Emphasis on Doppler sonography.
- Evaluation of other imaging tests.
Main Results:
- Diagnostic imaging plays a crucial role in identifying mesenteric ischemia.
- Doppler sonography offers valuable insights into mesenteric arterial flow.
- Specific imaging criteria aid in diagnosis.
Conclusions:
- Accurate diagnosis of mesenteric ischemia relies on appropriate imaging selection.
- Doppler sonography is a key tool for evaluating mesenteric arterial insufficiency.
- Understanding diagnostic criteria improves patient outcomes.
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