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Tissue-specific production of the third component of complement(C3) by vitamin D in bone
1Department of Biochemistry, School of Dentistry, Showa University, Tokyo, Japan.
Journal of Nutritional Science and Vitaminology
|January 1, 1992
Abstract:
The third component of complement (C3) is a protein produced by osteoblastic cells in response to 1 alpha,25(OH)2D3. The bone C3 appears to be involved in differentiation of bone marrow cells into osteoclasts in concert with other vitamin D-dependent factors. Further studies are needed to understand the precise role of C3 in bone.