[Correction of primary and secondary immunodeficiency with synthetic beta-carotene]
Abstract:
Immunotropic activity of artificial beta-carotene was studied in primary immune response to thymus-dependent antigen (sheep erythrocytes) using models of primary (inherent) and acquired (vinblastine-induced) immunodeficiency. The experiments were carried out using two strains of CBA and C57Black mice with dissimilar responses to the antigen. beta-Carotene was found to remove both acquired and inherent immunodeficiency. The immunostimulating effect of the drug studied appears to be related to the activated production of mediators, namely IL-2.
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