[Electrophoretic separation of glycosaminoglycans from different types of connective tissue and biological fluids]

Separation by means of electrophoresis on paper of glycoseaminoglycans from different types of human and animals connective tissue (bone tissue, synovial membrane of joints, skin and others) and from biological fluids (blood serum, urine, joint liquid) enabled to determine the ratio between sulphatated and nonsulphatated glycoseaminoglycans in normal conditions, in different pathological states and impairments of connective tissue structures. The method was found to be adequate for studies on quantitative and qualitative composition of glycoseaminoglycans and their metabolic products in pathologically altered connective tissue and biological fluids.