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Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice
Published on: October 16, 2014
[Radiologic evaluation of changes occurring in bone under the influence of gentamycin-septopal]
K Moroń1, S Misterka, U Dorobisz
1Katedra i Zakład Radiologii Akademii Medycznej, Wrocławiu.
Abstract:
On the basis of several-year experience it was acknowledged that in treatment of chronic blood-derived and traumatic inflammations of bones the introduction of chains of Septopal to treatment was an obvious progress. The changes occurring in the bones of the patients for whom Septopal was left for good in the marrow cavity under the influence of antibiotic were evaluated. The observation included 89 patients for whom X-ray examinations were made many times in various intervals. Initially the chains of antibiotic were surrounded with a thin layer of connective tissue, and after several new-generating osseous tissue grew into them. In none of the observed cases any reaction indicating recoil of the carrier of the antibiotic was noticed.
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