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[Value of intravesically instilled oxybutynin in refractory bladder hyperactivity. Study of 15 cases]
G Amarenco1, M A Adba, J Kerdraon
1Laboratoire d'Urodynamique et de Neurophysiologie, Hôpital Robert Ballanger, Aulnay-sous-Bois.
Abstract:
15 patients with neurogenic detrusor hyperactivity refractory to oral anticholinergics received a daily intravesical instillation of 5 mg of oxybutinin for 6 days. An improvement was observed clinically in 10 cases and on urodynamic parameters (60% increase in bladder capacity, doubling of the volume inducing an urge to void) in 12 cases. The mechanism of action is discussed.