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Nonfunctioning adrenocortical carcinoma.
S M Lele1, B V Mittal, I M Vora
1Dept of Pathology, Seth GS Medical College, Parel, Bombay, Maharashtra.
Journal of Postgraduate Medicine
|July 1, 1992
Summary
Adrenocortical carcinoma, a rare cancer, was diagnosed in a patient presenting with flank swelling and pain. Surgical removal and histopathology confirmed the diagnosis, with no signs of metastasis.
Area of Science:
- Oncology
- Pathology
Background:
- Adrenocortical carcinoma is a rare malignancy of the adrenal gland.
- Early diagnosis and treatment are crucial for patient outcomes.
Observation:
- A patient presented with left flank swelling, pain, weakness, and loss of appetite.
- Ultrasonography identified a left retroperitoneal mass.
- Radical surgery was performed, involving removal of the left kidney and spleen.
Findings:
- Histopathological examination confirmed adrenocortical carcinoma.
- The tumor cells exhibited a specific arrangement in columns and cords within a fibrovascular stroma.
- The Hough criteria score was 2.97, indicating malignancy.
- No evidence of metastasis was detected in the resected tissue.
Implications:
- This case highlights the importance of considering rare diagnoses in patients with non-specific symptoms.
- Radical surgical resection is a primary treatment modality for localized adrenocortical carcinoma.
- Accurate histopathological evaluation is essential for definitive diagnosis and staging.