Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Occupational exposure to cadmium and lung function.

G Cortona1, P Apostoli, F Toffoletto

  • 1Department of Occupational Medicine, Desio Hospital, Italy.

IARC Scientific Publications
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Progress to extinction: increased specialisation causes the demise of animal clades.

Scientific reports·2016
Same author

Medical Treatment for Acromegaly does not Increase the Risk of Central Adrenal Insufficiency: A Long-Term Follow-Up Study.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2016
Same author

The surveillance of occupational diseases in Italy: the MALPROF system.

Occupational medicine (Oxford, England)·2015
Same author

[Multiple self-notifications in 2000-2001 of occupational diseases to the registration system MALPROF].

La Medicina del lavoro·2014
Same author

Clinical and virological characteristics associated with severe acute hepatitis B.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2014
Same author

[The central role of the specialized physician in preventive care].

La Medicina del lavoro·2014

Occupational cadmium exposure in alloy factory workers led to increased residual volume (RV), indicating potential lung changes. However, standard lung function tests like FVC, FEV1, and diffusion capacity showed no significant differences.

Area of Science:

  • Occupational Medicine
  • Environmental Health
  • Pulmonary Physiology

Background:

  • Cadmium exposure is a known occupational hazard, particularly in industries involving metal alloys.
  • Understanding the long-term effects of cadmium on lung function is crucial for worker safety.

Purpose of the Study:

  • To assess the impact of occupational cadmium exposure on lung function in male workers.
  • To investigate the relationship between cumulative cadmium exposure and lung function parameters.

Main Methods:

  • Lung function tests including ventilation (FVC, FEV1), residual volume (RV), and diffusion capacity (TLCO, KCO) were performed on 69 male subjects.
  • Cumulative cadmium exposure was calculated based on years of employment and average atmospheric cadmium concentration.
  • A control group was used for comparison.

Related Experiment Videos

Main Results:

  • Cadmium-exposed subjects showed a moderate increase in mean residual volume (RV) by 8% compared to controls.
  • Workers with higher cumulative cadmium exposure exhibited a greater increase in RV (+10%).
  • No significant differences were found in forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), or diffusion capacity (TLCO, KCO).

Conclusions:

  • Occupational cadmium exposure may lead to subtle changes in lung volumes, specifically an increase in RV.
  • Standard lung function tests may not detect early-stage pulmonary effects of cadmium exposure.
  • Further research is needed to understand the clinical significance of RV changes in cadmium-exposed workers.