Related Experiment Video
Updated: Mar 31, 2026

A Single-Channel and Non-Invasive Wearable Brain-Computer Interface for Industry and Healthcare
Published on: July 7, 2023
The surveillance of occupational diseases in Italy: the MALPROF system
G Campo1, A Papale2, A Baldasseroni3
1Department of Work and Environmental Medicine, Epidemiology and Hygiene, National Institute for Insurance against Accidents at Work (INAIL), Via Ferruzzi 38-40, 00143 Rome, Italy, g.campo@inail.it.
Background:
Occupational diseases data can guide efforts to improve worker's health and safety.
Aims:
To describe MALPROF, the Italian system for surveillance of work-related diseases collected by the subregional Department of Prevention.
Methods:
The MALPROF system started in 1999 with contributions from Lombardy and Tuscany and spread in the following years to collect contributions from 14 out of the 20 Italian regions. MALPROF data were explored to follow-up work-related diseases and to detect emerging occupational health risks by calculating proportional reporting ratio (PRR), as in pharmacosurveillance. It classified work-related diseases according to economic sector and job activity in which the exposure occurred. Occupational physicians of the Italian National Health Service evaluate the possible causal relationship with occupational exposures and store the data in a centralized database.
Results:
From 1999 to 2012, the MALPROF system collected about 112000 cases of workers' diseases. In 2010, more than 13000 cases of occupational diseases were reported. The most frequently reported diseases were hearing loss (n = 4378, 32%), spine disorders (n = 2394, 17%) and carpal tunnel syndrome (n = 1560, 11%). The PRR calculated for cervical disc herniation, a disease whose occupational origin has to be studied, in 1999-2010 was 2.47 [95% confidence interval (CI) 1.76-3.47] for drivers and 36.64 (95% CI 22.03-60.93) for air transport workers.
Conclusions:
MALPROF is a sensitive system for identifying possible associations between occupational risks and diseases, it can contribute to the development of preventive measures, to evaluate the effectiveness of preventive interventions and to stimulate research on new occupational risks and diseases.
Insights
The Italian MALPROF system effectively monitors occupational diseases, identifying key risks like hearing loss and spine disorders. This surveillance aids in improving worker health and safety across various industries.
Area of Science:
- Occupational health and safety surveillance
- Public health informatics
- Epidemiology of work-related diseases
Background:
- Data on occupational diseases is crucial for enhancing worker health and safety initiatives.
- Effective surveillance systems are needed to track and manage work-related illnesses.
Purpose of the Study:
- To describe the MALPROF system, Italy's national surveillance program for work-related diseases.
- To outline the data collection and analysis methods used by the Department of Prevention.
Main Methods:
- The MALPROF system, initiated in 1999, expanded to include 14 Italian regions by 2012.
- Data analysis involved calculating the proportional reporting ratio (PRR) to identify occupational health risks.
- Work-related diseases were classified by economic sector and job activity, with causal relationships evaluated by occupational physicians.
Main Results:
- From 1999 to 2012, MALPROF collected approximately 112,000 cases of workers' diseases.
- The most frequently reported conditions were hearing loss (32%), spine disorders (17%), and carpal tunnel syndrome (11%).
- Elevated PRRs were observed for cervical disc herniation in drivers and air transport workers, suggesting potential occupational links.
Conclusions:
- MALPROF serves as a sensitive tool for detecting associations between occupational exposures and diseases.
- The system supports the development and evaluation of preventive measures for worker health.
- MALPROF can stimulate research into emerging occupational risks and diseases.
Related Concept Videos
Principles of Disease Surveillance
Investigation of Disease Outbreaks
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Secondary Healthcare System
Integrated Healthcare System
PPE Use in Healthcare Settings II: Doffing

