Related Experiment Video
Updated: Jul 15, 2026

11:49
Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
Published on: March 8, 2019
[Risk of dislocation and cataract formation in 240 IOGEL lenses. 4 years experiences]
Summary
IOGEL lens dislocation occurred in 5 of 240 patients after cataract surgery. Delayed Nd-YAG capsulotomy and capsular shrinkage increase dislocation risk, suggesting careful timing and technique are crucial for stable lens implantation.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Materials Science
Background:
- Cataract surgery involves implanting intraocular lenses (IOLs) to restore vision.
- IOGEL lenses are a type of foldable IOL implanted into the capsular bag.
- Complications such as IOL dislocation can impact visual outcomes.
Purpose of the Study:
- To evaluate the incidence and reasons for IOGEL lens dislocation after extracapsular cataract extraction.
- To identify risk factors associated with IOGEL lens instability.
- To provide recommendations for preventing IOL dislocation.
Main Methods:
- Prospective study of 240 patients undergoing cataract surgery with IOGEL lens implantation.
- Analysis of IOL dislocation events, including timing, associated procedures (e.g., Nd-YAG capsulotomy), and patient factors.
- Review of surgical records and patient outcomes.
Main Results:
- Five of 240 IOGEL lenses dislocated into the vitreous cavity.
- Dislocations occurred postoperatively, after Nd-YAG capsulotomy, and after surgical repositioning.
- Secondary cataract formation requiring Nd-YAG capsulotomy was noted in 33 patients.
- Capsular shrinkage and large capsular openings were identified as contributing factors to late dislocation.
- Eight patients required secondary anterior chamber lens implantation, with three explantations.
Conclusions:
- Primary stable placement of IOGEL lenses in the capsular bag is achievable.
- Late IOGEL lens dislocation can occur due to lack of adhesion to capsular sheets and postoperative capsular shrinkage.
- Recommendations include delaying Nd-YAG capsulotomy until at least 6 months postoperatively, limiting its diameter to 4 mm, and avoiding IOGEL implantation in cases of intraoperative capsular rupture.
Related Concept Videos
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

