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Heart in adrenal diseases.

T Janota1, J Hradec, J Král

  • 1IIIrd Department of Internal Medicine, Charles University, 1st School of Medicine, Prague, Czechoslovakia.

Cor Et Vasa
|January 1, 1992
PubMed
Summary

Cardiac changes in endocrine disorders like phaeochromocytoma, primary hyperaldosteronism, and Cushing syndrome were assessed using echocardiography. Echocardiographic abnormalities in these conditions resolved after treatment, indicating reversible cardiac effects.

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Area of Science:

  • Cardiology
  • Endocrinology
  • Medical Diagnostics

Background:

  • Cardiac alterations in endocrine disorders are not fully understood.
  • Limited literature exists on echocardiographic findings in phaeochromocytoma, primary hyperaldosteronism, and Cushing syndrome.

Purpose of the Study:

  • To review existing literature on cardiac changes in these endocrine diseases.
  • To present novel echocardiographic findings in patients with phaeochromocytoma, primary hyperaldosteronism, and Cushing syndrome.

Main Methods:

  • Literature review on cardiac manifestations of the specified endocrine disorders.
  • Echocardiographic assessment of cardiac structure and function in affected patients.
  • Comparison of findings with control groups and post-treatment evaluations.

Main Results:

  • Phacochromocytoma: Mild interventricular septum thickening and increased left ventricular mass without significant functional impairment.
  • Primary hyperaldosteronism: Slight posterior left ventricular wall thickening and increased left ventricular mass index.
  • Cushing syndrome: Tendency towards concentric left ventricular hypertrophy.
  • Observed echocardiographic changes were reversible post-treatment in all conditions.

Conclusions:

  • Endocrine disorders like phaeochromocytoma, primary hyperaldosteronism, and Cushing syndrome can induce subtle cardiac changes.
  • Echocardiography is valuable in detecting these cardiac alterations.
  • The observed cardiac changes are generally reversible upon successful treatment of the underlying endocrine condition.

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