[Pathophysiologic mechanisms of cardiorespiratory system dysfunction in high school children with chronic obstructive...

The basic indices of the cardiorespiratory system function, gas exchange, regional pulmonary functions have been studied. It is stated that a group of children with a higher level of oxygen consumption (hyperergic type) as against a control group is characterized by disorder in permeability of terminal branches of a bronchial tree, by the development of acute obstructive emphysema, increase in alveolar ventilation with relative decrease in minute blood volume, arterial hypoxemia with possible emergence of tissue hypoxia. A decrease in permeability of large bronchi were observed in a group of children with a low level of oxygen consumption (hypoergic type). Due to this decrease the hypoventilation zones appeared. It caused the development of arterial hypoxemia, but a risk of the tissue hypoxia emergence was insignificant.