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Updated: Aug 7, 2026

Visualization and Analysis of Blood Flow and Oxygen Consumption in Hepatic Microcirculation: Application to an Acute Hepatitis Model
Published on: August 4, 2012
[Disturbances in biliary secretion during tissue hypoxia and attempts at their corrections]
T M Hovorukha1, A I Nazarenko, L I Zhalilo
1A.A. Bogomoletz Institute of Physiology, National Academy of Science of Ukraine, Kiev.
Abstract:
In acute experiments on rats in vivo the stimulating effects of hydrophilic cholic acids (CA and UDCA) on the bilification and their inhibiting by rotenone have been shown. The secretion of CA and UDCA under rotenone have been determined to be activated. The mechanisms of the influence of the cholic acids on the secretory function of the hepatocytes have being discussed. It has been concluded that NADH-dehydrogenase link in the respiratory chain is not involved in the activating effects by CA and UDCA.
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