Related Experiment Video
Updated: Sep 19, 2026

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds
Published on: February 23, 2024
The occurrence of changes resembling the inflammatory in skin injured and incubated after excision
Abstract:
Observations are reported on the changes which occurred in excised rabbit and human skin after mild trauma and incubation at body temperature. These changes resembled those of chronic inflammation, in that perivascular and diffuse infiltration by histiocytes occurred in the corium and subcutaneous tissue, but they developed within a few hours. The experiments have shown that even after removal from the body certain tissue elements may retain the ability to react with proliferative changes in response to tissue injury if kept under artificially simulated physiological conditions. The possible significance of these changes in relation to the inflammatory process is discussed.
Related Concept Videos
Inflammatory Response II: Inflammatory Exudate and Tissue Repair
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the exudate's...
Inflammatory Response
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
Healing II: Complications
Inflammation
Clinical Applications of Epidermal Stem Cells
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
