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The cytotoxic effects of denture base resin sealants
C A Lefebvre1, G S Schuster, D W Richardson
1Department of Prosthodontics, Medical College of Georgia, School of Denistry, Augusta 30912.
The International Journal of Prosthodontics
|November 1, 1992
Abstract:
Previous studies have shown that light-polymerized denture base resins have a cytotoxic effect on oral epithelial cells. The purpose of this in vitro study was to examine the effects of two denture base resin sealants when used on three light-polymerized denture base resins. Sample disks were examined for their effect on protein synthesis. Results indicate that one sealant protected the cells against toxic effects of the materials (P < .05), while one sealant enhanced toxicity up to 88% above that attributed to the resin alone.