[The characteristics of the reparative process in the muscles when deprived of their functional loads]

The time course of repair process in the tonic soleus and phasic gastrocnemius muscles of the head-down tail-suspended rats being traumatized directly prior to suspension or immediately after it. During first, suspension, the animals have been studied on the 17th suspension day and in the second 14-day suspension they were tested on the 14th and 17th post-traumatic days. It was indicated that the suspension results in muscle atrophy with a severely affected m. gastrocnemius loosing more than 40% of its mass. Under the effect of atrophy-induced factors in both muscles there equally occurred an inhibition of both the formation of connective stroma of repair field and the isolation of myoblasts from dedifferentiated muscular fibers due to which an extremely small-size repair field with the irregularly oriented muscular fibers and myoblasts has been originated.