Related Experiment Videos
[Urinary citrate determination in normal persons and in patients with recurrent urinary calculi]
I de L Noronha1, A Andriolo, E Wroclawski
1Grupo Multidisciplinar de Estudos da Calculose Urinária, Hospital das Clínicas da Faculdade de Medicina, Universidade de São Paulo.
Revista Do Hospital Das Clinicas
|January 1, 1992
Abstract:
The presence of citric acid in urine and its ability to bind calcium ions forming a soluble complex are well recognized and has led to the suggestion that citric acid may play an important role in preventing renal calcium stone disease. In this study the 24-hour urinary excretion was measured with a specific enzymatic method in 48 normal subjects and in a group of 46 non selected patients with recurrent urolithiasis. Hypocitraturia was detected in 18/46 patients (39.1%) and was the unique metabolic abnormality in 6 (13%).