Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Cardiac and plasma catecholamine response to dynamic exercise in hyperthyroidism].

H Kitamura1, T Kinugawa, H Miyakoda

  • 1First Department of Internal Medicine, Tottori University School of Medicine, Yonago.

Journal of Cardiology
|January 1, 1992
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

FDG-PET predicts treatment efficacy and surgical outcome of pre-operative chemoradiation therapy for resectable and borderline resectable pancreatic cancer.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2017
Same author

A retrospective analysis of the clinical effects of neoadjuvant combination therapy with full-dose gemcitabine and radiation therapy in patients with biliary tract cancer.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2017
Same author

De novo malignancy after pancreas transplantation in Japan.

Transplantation proceedings·2015
Same author

miR-320c regulates gemcitabine-resistance in pancreatic cancer via SMARCC1.

British journal of cancer·2013
Same author

Biosynthesis of IL-8 and endothelin-1,2 by immortal simian virus 40 tsA-transformed human endothelial cells.

Oncology reports·2011
Same author

MicroRNA-21 induces resistance to the anti-tumour effect of interferon-α/5-fluorouracil in hepatocellular carcinoma cells.

British journal of cancer·2010

Hyperthyroidism causes a hyperdynamic cardiac state during exercise due to altered sympathoadrenal responses. Antithyroid therapy reverses these changes, normalizing heart rate and catecholamine levels.

Area of Science:

  • Cardiovascular Physiology
  • Endocrinology
  • Exercise Science

Context:

  • Hyperthyroidism is associated with a hyperdynamic cardiovascular state.
  • Sympathoadrenal system activity is crucial for regulating cardiac function during exercise.
  • Understanding these responses in hyperthyroidism is vital for patient management.

Purpose:

  • To investigate cardiac and sympathoadrenal responses to dynamic exercise in hyperthyroid patients.
  • To compare these responses with age-sex matched controls.
  • To assess the reversibility of these changes after achieving euthyroid state.

Summary:

  • Hyperthyroid patients exhibited shorter exercise duration, higher resting and exercise heart rates, and systolic blood pressures compared to controls.

Related Experiment Videos

  • Plasma norepinephrine levels were lower, while epinephrine levels during early exercise were higher in hyperthyroid patients.
  • Achieving a euthyroid state post-therapy normalized cardiac and sympathoadrenal responses to exercise.

    • Impact:

    • Hyperthyroidism induces a hyperdynamic cardiac state during exercise, characterized by decreased sympathetic nervous activity and increased adrenomedullary response.
    • These exercise-induced cardiovascular and sympathoadrenal modifications are reversible with effective antithyroid treatment.
    • Findings highlight the importance of managing thyroid status for optimizing exercise capacity and cardiovascular health.