Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Oat bran as lipid-lowering agent?].

M Longauer1, P Erne, E Schmidt

  • 1Dept. Innere Medizin, Medizinische Universitäts-Poliklinik, Kantonsspital, Basel.

Schweizerische Rundschau Fur Medizin Praxis = Revue Suisse De Medecine Praxis
|February 18, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Calculation of the resistance to CSF outflow.

Journal of neurology, neurosurgery, and psychiatry·2003
Same author

Protein A immunoadsorption: a novel and effective adjuvant treatment of severe pemphigus.

The British journal of dermatology·2003
Same author

Gene structure of human carbamylphosphate synthetase 1 and novel mutations in patients with neonatal onset.

Human mutation·2003
Same author

[Diagnosis and follow-up in glaucoma patients using the Heidelberg retina tomograph].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2003
Same author

Ensembl 2002: accommodating comparative genomics.

Nucleic acids research·2003
Same author

[Transillumination technique in difficult intubations in heart surgery].

Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS·2002
Same journal

[In Process Citation]

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis·1999
Same journal

[A case from practice (306). Erythema (chronicum) migrans (stage I of Lyme borreliosis].

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis·1994
Same journal

[A case from practice (305). Recurrent erysipelas--tinea pedis et unginum--chronic venous insufficiency].

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis·1994
Same journal

[Neuroendocrine tumors of the stomach (stomach carcinoid)].

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis·1994
Same journal

[Time of drug intake in hypertension and angina pectoris. A controlled monitoring study].

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis·1994
Same journal

[Mental suffering IN patients with parkinsonism].

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis·1994
See all related articles

Oat bran, a soluble plant fiber, moderately reduced serum cholesterol in hypercholesterolemia patients. While effects diminished slightly over nine weeks, it showed consistent benefits for high-risk individuals.

Area of Science:

  • Cardiovascular Health
  • Nutritional Science
  • Dietary Fiber Research

Background:

  • Hypercholesterolemia is a primary risk factor for ischemic heart disease and atherosclerosis.
  • Water-soluble plant fibers can bind intestinal cholesterol, offering a potential dietary intervention.
  • Oat bran is a recognized source of highly water-soluble fiber.

Purpose of the Study:

  • To investigate the impact of oat bran consumption on serum cholesterol levels.
  • To assess the efficacy of a daily 50g oat bran intervention over nine weeks.
  • To evaluate effects in the general population and specific high-risk subgroups.

Main Methods:

  • A nine-week intervention study involving 14 volunteers (39-67 years) with hypercholesterolemia.
  • Daily intake of 50g of oat bran.

Related Experiment Videos

  • Monitoring of serum cholesterol concentrations at six and nine weeks.
  • Subgroup analysis for males, hypercholesterolemia, and essential hypertension.

    • Main Results:

    • A modest, significant reduction of 4.2% in serum cholesterol observed at six weeks (p<0.05).
    • Efficacy decreased by nine weeks (3.2% reduction, p=n.s.), suggesting potential compliance issues.
    • More consistent cholesterol reduction (5.6%, p<0.05) noted in high-risk subgroups (males, hypercholesterolemia, hypertension).

    Conclusions:

    • Daily oat bran intake can lead to a modest reduction in serum cholesterol levels.
    • The cholesterol-lowering effect may be more pronounced and consistent in individuals at high risk for cardiovascular disease.
    • While well-tolerated, long-term compliance might influence the sustained efficacy of oat bran interventions.