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Sclerosing lipogranuloma of the orbit after periocular steroid injection
Ari D Abel1, J Andrew Carlson, Sophie Bakri
1Department of Ophthalmology, Lion's Eye Institute, Albany Medical Center, Albany, New York 12208, USA.
Purpose:
To report the clinical and histopathologic findings of a large sclerosing lipogranuloma of the orbit arising after a sub-Tenon's corticosteroid injection.
Design:
Interventional case report and review of the literature.
Methods:
A complete ocular and systemic evaluation was performed on a 81-year-old patient, who developed a large orbital mass subsequent to a periocular corticosteroid injection producing proptosis, ptosis, and ocular motility impairment. The lesion was biopsied and submitted for histopathologic analysis.
Main Outcome Measures:
Orbital, computed tomography, and histopathologic findings.
Results:
Histopathologic examination revealed lipogranulomatous inflammation. Specifically, this type of reaction was consistent with a diagnosis of sclerosing lipogranuloma.
Conclusions:
It is extremely rare to find a large granulomatous orbital lesion arising subsequent to a periocular corticosteroid injection. Only one case has been reported in the English-language literature to date. It is important to include this type of lesion in the differential diagnosis of an orbital mass seen after the injection of periocular corticosteroids.
