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Pulmonary cestodiasis in a cynomolgus monkey (Macaca fascicularis)
1Louisiana State University Eye Center, New Orleans 70112.
Laboratory Animal Science
|April 1, 1992
Summary
A cynomolgus monkey in a surgical study died unexpectedly. Necropsy revealed cestode cysts resembling tetrathyridia, suggesting a potential parasitic cause, though further identification is needed.
Area of Science:
- Veterinary Pathology
- Primate Medicine
- Parasitology
Background:
- Cestodiasis is historically common in primates, with varying degrees of clinical impact.
- Larval cestodes can cause significant tissue damage (e.g., hydatid, cysticercus cysts) or minimal effects (e.g., tetrathyridia).
Observation:
- A seemingly healthy cynomolgus monkey experienced sudden death 3 hours post-surgery, attributed to respiratory arrest.
- Necropsy revealed small (1-3 mm) cysts containing larvae (2-5 mm).
Findings:
- The larvae were not definitively identified but morphologically resembled tetrathyridia of the genus Mesocestoides.
- The presence of these larval cestodes in a primate surgical model warrants further investigation.
Implications:
- This case highlights the potential for subclinical parasitic infections in research primates.
- Understanding cestode burdens is crucial for interpreting physiological parameters and outcomes in primate studies.
- Further research is needed to identify the specific cestode species and its pathogenic potential in this host.