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Inclusion body myositis: its relative frequency in elderly people
M L Maat-Schieman1, J D Macfarlane, G T Bots
1Department of Neurology, University Hospital, Leiden, The Netherlands.
Clinical Neurology and Neurosurgery
|January 1, 1992
Summary
Inclusion body myositis (IBM) is the most common inflammatory myopathy in elderly patients. This finding suggests caution with steroid treatments in this demographic due to potential hazards.
Area of Science:
- Neurology
- Rheumatology
- Geriatrics
Background:
- Inclusion body myositis (IBM) is a steroid-resistant inflammatory myopathy.
- IBM predominantly affects the elderly, a population where steroid treatment poses significant risks.
Purpose of the Study:
- To determine the relative frequency of IBM among elderly patients diagnosed with inflammatory myopathy.
- To inform clinical management strategies for inflammatory myopathies in older adults.
Main Methods:
- Retrospective study of patients over 50 years old diagnosed with inflammatory myopathy between 1980 and 1991.
- Analysis of diagnostic data to identify cases of Inclusion Body Myositis.
Main Results:
- Inclusion body myositis was identified in 9 out of 15 patients (60%) with inflammatory myopathy.
- A diagnosis of IBM was strongly suspected in an additional 2 patients.
Conclusions:
- Inclusion body myositis is the most frequent inflammatory myopathy observed in the elderly population.
- The high prevalence of IBM in the elderly supports a cautious approach to steroid therapy in this group.