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Histopathologic and cytochemical characteristics of interval breast carcinomas from the Stockholm Mammography
A von Rosen1, J Frisell, R Nilsson
1Dept. of Surgery, Karolinska Institute and Hospital, Stockholm, Sweden.
Acta Oncologica (Stockholm, Sweden)
|January 1, 1992
Abstract:
Combined morphological and cytochemical malignancy grading in addition to tumor stage was applied to assess the malignant potential of so-called interval carcinomas from the Stockholm randomized mammography screening study. Only interval carcinomas surfacing within two years from screening were included. Fifty-four percent of the tumors were in stage I and 46% of the carcinomas eligible for DNA analysis were diploid, i.e. low-malignant. An overrepresentation of prognostically unfavorable tumor characteristics was found only within the subgroup 'true' and 'early' interval cancer.