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Related Experiment Videos

Autonomic dysfunction in peripheral nerve disorders.

J G McLeod1

  • 1Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

Current Opinion in Neurology and Neurosurgery
|August 1, 1992
PubMed
Summary
This summary is machine-generated.

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Most peripheral neuropathies impact the autonomic nervous system. While autonomic dysfunction is significant in conditions like diabetes, it

Area of Science:

  • Neurology
  • Autonomic Neuroscience

Background:

  • Peripheral neuropathy frequently involves the autonomic nervous system.
  • Autonomic dysfunction's clinical significance varies widely among neuropathic conditions.

Purpose of the Study:

  • To highlight the prevalence of autonomic nervous system involvement in peripheral neuropathy.
  • To emphasize the diagnostic necessity of assessing both sympathetic and parasympathetic functions.

Main Methods:

  • Review of conditions causing peripheral neuropathy.
  • Analysis of the clinical impact of autonomic disturbances.

Main Results:

  • Autonomic nervous system dysfunction is a common feature of peripheral neuropathy.
  • Clinically significant autonomic dysfunction occurs in specific conditions like diabetes, amyloidosis, Guillain-Barré syndrome, and porphyria.

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  • In many neuropathies, autonomic disturbances are minor.

    • Conclusions:

    • Autonomic dysfunction is a widespread consequence of peripheral neuropathy.
    • Comprehensive clinical testing of autonomic (sympathetic and parasympathetic) function is crucial for accurate diagnosis.