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Updated: Sep 17, 2026

Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
Published on: January 19, 2019
Antagonism and synergy of antigens
Knowledge of the phenomena of antigen antagonism and synergy is still very limited, and their effects cannot yet be measured quantitatively. However, it appears from this consideration of the conditions under which antigens may influence one another and of the practical application of what is known of these conditions that synergistic effects of antigens may well play a more important role in preventive vaccination than was formerly supposed.
Knowledge of the phenomena of antigen antagonism and synergy is still very limited, and their effects cannot yet be measured quantitatively. However, it appears from this consideration of the conditions under which antigens may influence one another and of the practical application of what is known of these conditions that synergistic effects of antigens may well play a more important role in preventive vaccination than was formerly supposed.
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