Restoration of the lateral sinus wall using a collagen type I membrane for guided tissue regeneration

A collagen type I membrane prepared from bovine pericard was used to restore and thicken the lateral sinus wall after resection in 6 Göttingen minipigs. One rehydrated collagen type I membrane was placed on the intact sinus mucosa. A hydroxyapatite block was placed on this membrane and covered with a second membrane. After 6 months there was complete, bony regeneration in the space between the 2 membranes and thickening of the new bone plate compared to the untreated control side. This study shows that a collagen membrane can be applied for guided tissue regeneration.