[Biogenic amines in the brain structures of rats from genetically diverse strains under stress]

The content was studied of biogenic amines and their metabolites (by the method of high-effective fluid chromatography electrochemical detection) in the reticular formation of the midbrain, locus coeruleus and sensorimotor cortex in the rats of Wistar and August lines, differing in the behaviour in the open field, in conditions of immobilization stress. The dependence was revealed of the biogenic amines level on the animals genotype and individual characteristics. Most probably, the level of biogenic amines metabolism in central brain structures determines the stability of the animals against emotional stress.