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Does Hakka ethnic group have higher incidence of thalassemia traits in Taiwanese population?
C C Chien1, C K Lin, M L Jiang
1Department of Internal Medicine, Veterans General Hospital-Taipei, Taiwan, R.O.C.
The purpose of this survey is to find out whether Hakka group has higher incidence of thalassemia traits in our population. A total of 1,115 healthy employees from a company were screened by complete blood count (CBC) with indices. Those subjects with mean corpuscular volume (MCV) less than 80 fl were further evaluated by hemoglobin electrophoresis and modified hemoglobin H (Hb H) inclusion staining to confirm the diagnosis of beta- and alpha-thalassemia traits, respectively. We evaluated and compared the crude occurrence rates of thalassemia traits in Hakka, non-Hakka, and Taiwanese. Subjects with one or both Hakka parents had higher crude incidence of alpha-thalassemia traits than other groups of subjects, but this phenomenon wasn't found in beta-thalassemia traits.
The purpose of this survey is to find out whether Hakka group has higher incidence of thalassemia traits in our population. A total of 1,115 healthy employees from a company were screened by complete blood count (CBC) with indices. Those subjects with mean corpuscular volume (MCV) less than 80 fl were further evaluated by hemoglobin electrophoresis and modified hemoglobin H (Hb H) inclusion staining to confirm the diagnosis of beta- and alpha-thalassemia traits, respectively. We evaluated and compared the crude occurrence rates of thalassemia traits in Hakka, non-Hakka, and Taiwanese. Subjects with one or both Hakka parents had higher crude incidence of alpha-thalassemia traits than other groups of subjects, but this phenomenon wasn't found in beta-thalassemia traits.