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Effect of cholesterol oxidation on (Na+, K+) ATPase activity of erythrocyte membranes
Experientia
|January 1, 1976
Abstract:
By incubation of human erythrocyte ghosts with cholesterol oxidase (EC 1.1.3.6) part of the cholesterol of the membrane is replaced by 4-cholesten-3-one. This alteration in the sterol composition is accompanied by an inhibition of the (Na+, K+) ATPase of the erythrocyte membrane.