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Effect of Pre-S1 protein on the long-term cultures of human lymphocytes after hepatitis B immunization
Z Sułowska1, H Tchórzewski, M Sidorkiewicz
1Microbiology and Virology Center, Polish Academy of Sciences, Lódź.
Archivum Immunologiae Et Therapiae Experimentalis
|January 1, 1992
Abstract:
Long-term cultured T-cells, reactive to Pre-S1 protein, were developed from peripheral blood mononuclear cells (PBMC) of individuals after recovery from hepatitis B infection and of vaccine recipients by in vitro Pre-S1 protein stimulation in the presence of IL-2. The proliferative responses to Pre-S1 protein and functional activities of cultured T-cells were characterized.