Related Experiment Videos
A skin irritant phorbol ester from Euphorbia cooperi N E Br
1Department of Pharmacy University of Zimbabwe, Mount Pleasant, Harare.
The Central African Journal of Medicine
|December 1, 1992
Abstract:
From the fresh latex of Euphorbia cooperi N E Br was isolated by partition and chromatographic methods, a diterpene ester 12-deoxyphorbol-16-isobutyrate-13-tigliate. The phorbol ester exhibited highly irritant activity on the mouse ear. Since skin irritancy is an indication of possible tumour promotion, the use of this plant as a medicine should be discouraged.