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[Cutaneous infection by mycobacterium marinum: case report]
R Guarda1, W Gubelin, J Gajardo
1Clínica Alemana, Hospital Clínico y Facultad de Medicina, Universidad de Chile.
Revista Medica De Chile
|September 1, 1992
Summary
A fish handler developed skin nodules caused by Mycobacterium marinum infection. Treatment with ciprofloxacin initially worked but relapsed, with a cure achieved using cotrimoxazole and topical kanamycin.
Area of Science:
- Dermatology
- Infectious Diseases
- Microbiology
Background:
- Mycobacterium marinum infections, often acquired from aquatic environments, can cause skin lesions.
- Nontuberculous mycobacterial infections pose diagnostic and therapeutic challenges.
Observation:
- A 45-year-old male fish handler presented with painless, nodular plaques on both hands.
- Histopathology revealed a dermal mononuclear infiltrate with granulomata.
- Cultures confirmed Mycobacterium marinum infection.
Findings:
- Initial treatment with ciprofloxacin showed partial success but was followed by relapse upon discontinuation.
- Definitive treatment involved a combination of oral cotrimoxazole and topical kanamycin.
- This combination therapy led to a complete cure.
Implications:
- Highlights the importance of considering Mycobacterium marinum in individuals with aquatic exposure and hand lesions.
- Suggests that combination therapy may be necessary for persistent or relapsed cases of fish tank granuloma.
- Emphasizes the need for prolonged treatment and careful monitoring for M. marinum infections.