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Use of MAC-ELISA for evaluation of yellow fever vaccination
R M Nogueira1, H G Schatzmayr, M P Miagostovich
1Instituto Oswaldo Cruz, Departamento de Virologia, Rio de Janeiro, Brasil.
Revista Do Instituto De Medicina Tropical De Sao Paulo
|September 1, 1992
Abstract:
An evaluation of the IgM antibody immune response against yellow fever using strain 17D was carried out by MAC-ELISA and PRNT. The results showed an agreement of 97% between both tests and the authors conclude that MAC-ELISA can be used as a specific and sensitive assay to replace the PRNT for detecting yellow fever antibodies in human sera, after vaccination programs.