Immunoregulatory properties of seminal plasma: perspective and prospective considerations

Perspective and prospective considerations of the immunoregulatory properties of seminal plasma and their biological and/or clinical relevance are presented. Further understanding of the interactions of the immune system with exocrine products of the male reproductive system may contribute to improvements in reproductive health and to an understanding of the antithetical aspects of the immune response represented by such biological phenomena as insemination, pregnancy and malignancy.