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Published on: October 25, 2024
Fertility Preservation for Children and Adolescents with Cancer
Kristine S Corkum1, Amanda Buchanan2, Erin E Rowell3
1Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Fertility Preservation and Reproductive Late Effects Program, Children's Hospital Colorado, Aurora, CO, USA.
Abstract:
Survivors of pediatric cancer are at an increased risk for infertility and premature hormonal failure. Surgeons caring for children with cancer are important advocates for infertility risk assessment and can perform appropriate fertility preservation (FP) procedures. FP options in male individuals and female individuals vary by pubertal status and include nonexperimental (oocyte harvest, ovarian tissue cryopreservation, and sperm cryopreservation) and experimental (testicular tissue cryopreservation) options. This review summarizes infertility risk assessment and FP options, explores important factors in access to pediatric FP, and highlights the current status of FP research.
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