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[Blood-group systems ABO and RH in the Kenyan population]
J Lyko1, H Gaertner, J N Kaviti
1Katedry i Kliniki Chorób Wewnetrznych i Medycyny Wsi Akademii Medycznej im. M. Kopernika.
Folia Medica Cracoviensia
|January 1, 1992
Summary
This study analyzed blood groups in 38,898 Kenyan donors, finding Blood Group O (47.4%) and Rh (D) positive (96.1%) were most common. These findings highlight significant ABO and RhD allele frequencies in the Kenyan population.
Area of Science:
- Hematology
- Population Genetics
Context:
- Blood group and Rh (D) antigen distribution is crucial for transfusion medicine and understanding population genetics.
- Previous data on these distributions in Kenyan populations is limited, necessitating updated research.
Purpose:
- To determine the prevalence of ABO and Rh (D) blood groups among healthy adult blood donors in Kenya.
- To calculate gene frequencies for ABO and Rh (D) alleles.
- To compare findings with existing data from other African populations.
Summary:
- A retrospective analysis of 38,898 healthy adult blood donors in Kenya revealed Blood Group O at 47.4%, A at 26.2%, B at 22.0%, and AB at 4.4%.
- Rh (D) positive donors constituted 96.1%, with a 0.75% Du positive variant, while Rh (D) negative was 3.9%.
- Gene frequencies were calculated as p(A)=0.168, q(B)=0.142, r(0)=0.690, D positive=0.804, and D negative=0.196.
Impact:
- The study establishes a current baseline for ABO and Rh (D) blood group frequencies in a significant Kenyan cohort.
- Results provide valuable data for transfusion services, patient management, and anthropological studies in East Africa.
- Comparison with other populations aids in understanding migration patterns and genetic diversity across Africa.