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[Sensitivity and specificity of mouse peritoneal macrophages in the diagnosis of Chlamydia trachomatis infections]
F Guerra-Infante1, F J García-Zaragoza, J L Arrendondo-García
1Departamento de Infectología e Inmunología, Instituto Nacional de Perinatología, México, D.F.
Abstract:
We analyzed the sensitivity and specificity of mouse peritoneal macrophages (MPM) for the diagnosis of infection by Chlamydia trachomatis. Fifty seven samples were studied, 25 of them were from cervix and 32 were from bronchial aspiration, resulting 29 positive by immunofluorescence in McCoy cells and only 16 in MPM. The sensitivity and specificity for MPM were 55% and 96% respectively. We concluded that McCoy cells are the election cells for the diagnosis of Chlamydia infection. However, the MPM can be useful in the recuperation of this microorganism, if no other method is available.