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Surgical jaundice in infants: other than biliary atresia
1Department of Surgery, Children's Hospital, Denver, CO.
Insights
Infantile surgical jaundice after biliary atresia is often caused by common bile duct perforation or choledochal cysts. Treatment varies from peritoneal drainage for perforation to surgical excision for cysts.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Neonatal Medicine
Background:
- Biliary atresia is a leading cause of surgical jaundice in infants.
- Identifying the specific cause of jaundice is crucial for timely and appropriate intervention.
Purpose of the Study:
- To outline the common causes of surgical jaundice in infants following biliary atresia.
- To describe the typical presentation and recommended treatment for each identified cause.
Main Methods:
- Review of common etiologies of surgical jaundice in infants post-biliary atresia.
- Description of clinical presentation and diagnostic considerations.
- Summary of established treatment modalities for each condition.
Main Results:
- Common bile duct perforation, choledochal cyst, bile plug syndrome, and miscellaneous congenital lesions are the primary causes, in descending order of frequency.
- Perforation often presents with bilious ascites, treated by peritoneal drainage.
- Choledochal cysts require surgical excision.
- Bile plug syndrome typically resolves spontaneously, with occasional need for irrigation.
- Miscellaneous lesions are generally amenable to surgical correction.
Conclusions:
- Prompt diagnosis and tailored treatment of these lesions are essential for managing infantile surgical jaundice.
- Understanding the differential diagnoses and their specific management strategies improves patient outcomes.
Abstract:
After biliary atresia, the lesions responsible for surgical jaundice in the infant are perforation of the common bile duct, choledochal cyst, bile plug syndrome, and miscellaneous congenital lesions in descending order of frequency. Perforation of the common bile duct commonly presents with an insidious onset of bilious ascites and is best treated by simple peritoneal drainage. Choledochal cyst usually presents later in childhood but presents in infancy if obstruction of the biliary tree is complete or near complete. Excision is the treatment of choice. Any condition leading to alteration in bile composition may cause bile plug syndrome. Spontaneous resolution is the rule: occasionally, intraoperative irrigation is necessary. Most miscellaneous lesions lend themselves to operative correction.
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