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[Changes in plasma lipoproteins in Mediterranean boutonneuse fever]
A el Amrani Marini1, P Aranegui Lasuen, J M Barcelo Valcarcel
1Service de Médecine interne, HG Virgen de las Nieves, Granada, Espagne.
Abstract:
We report 25 cases of boutonneuse fever with, in the acute phase, an increase of plasma transaminases, triglycerides and apoprotein B levels, a decrease of total, HDL and LDL cholesterol and a decrease of apoprotein A. These changes disappeared 1 to 4 weeks after the beginning of treatment. They might be due to a reduced activity of lecithin-cholesterol acetyltransferase and lipoprotein lipase, probably caused by the hepatic and vascular disorders frequently found in this disease.