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Updated: Aug 3, 2026

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Use of a Monocyte Monolayer Assay to Evaluate Fcγ Receptor-mediated Phagocytosis
Published on: January 2, 2017
[Expression of low-affinity Fc epsilon receptors on circulating monocytes in patients with inflammatory rheumatic
H Becker1, P Potyka, A Langrock
1Medizinische Klinik III und Poliklinik, Universität Giessen.
Abstract:
In patients with scleroderma, high proportions of circulating CD23+ monocytes could be detected by FACS analysis as compared with controls. Supernatants obtained from lymphocytes yielded high amounts of interleukin-4-(IL-4-)like activity. The results suggest that IL-4 contributes to monocyte activation in scleroderma. There were no correlations with serum IgE, or numbers of naive and memory-CD4+ lymphocytes.
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