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Updated: Jun 24, 2026

Rapid Generation of Amyloid from Native Proteins In vitro
Published on: December 6, 2013
Localised alveolar-septal amyloidosis with hypersensitivity pneumonitis
R Orriols1, J L Aliaga, M J Rodrigo
1Servei de Pneumologia, Hospital General Universitari Vall d'Hebron, Barcelona, Spain.
Abstract:
Localised alveolar-septal amyloidosis has been thought irreversible. A woman exposed to the dust of sea-snail shells during the manufacture of nacre buttons had clinical and immunological features typical of hypersensitivity pneumonitis; however, transbronchial lung biopsy showed alveolar-septal amyloidosis. There was no evidence of other diseases known to be associated with amyloidosis, nor were amyloid deposits found in other organs. After a year without exposure to the antigen there was no trace of either pneumonitis or amyloidosis.
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