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Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods
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Placental malaria and pregnancy outcome

S E Ibhanesebhor1, A A Okolo

  • 1University of Benin Teaching Hospital, Department of Child Health, Nigeria.

International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics
|April 1, 1992
PubMed

Malaria parasitemia was assessed in 312 placentae of singleton deliveries in Benin. The prevalence rate was 45.19%. The dominant infecting specie was Plasmodium falciparum. High density parasitemia of placental smear in 44.68% was associated with preterm delivery, low birthweight, intrauterine growth retardation and neonatal mortality. Placental histological diagnosis of malaria in 57.69% was more frequently associated with intrauterine growth retardation. Extraplacental parasitemia decreased but intraplacental parasitemia increased with gestational age.

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